봉독약침과 녹용약침이 MIA 유도 골관절염 흰쥐에 미치는 영향
Effects of Bee Venom and Cervi Cornu Parvum Pharmacoacupuncture in Monosodium lodoacetate(MIA)-Induced Osteoarthritis Rat
김환영 (동신대학교 한의과대학) , 최진봉 ( 동신대학교 한의과대학)
| 저널명 | 韓方再活醫學科學會誌 | 기관명 | 한방재활의학과학회 |
|---|---|---|---|
| ISSN | 1229-1854 | 발행일 | 2010-01-31 |
| 권호 | 제 20권 제 1호 | 페이지 | 61-77 |
| 조회수 | 450 | ISBN |
초록
한글초록
한글 초록 없음
영어초록
Objectives :
The purpose of this study was to investigate the effects of Bee Venom (BV) and Cervi Cornu Parvum pharmacoacupuncture (CC) in monosodium iodide induced arthritis rats.
Methods :
The subjects were divided into 5 groups ; Normal, Control (no treatment after MIA), BV (Bee Venom pharmacoacupuncture 100 ㎕ daily at Dokbi (ST35) after inducing MIA), CC (Cervi Cornu Parvum pharmacoacupuncture 100 ㎕ daily at Dokbi (ST35) after inducing MIA) and BV+CC (Bee Venom pharmacoacupuncture and Cervi Cornu Parvum pharmacoacupuncture 100 ㎕ daily at Dokbi (ST35) after inducing MIA).
After each operation, the present author observed the motor behavior recovery, hematological (Prostaglandin E2, AST, ALT), histological and immunological changes. Rats were tested at the 7th, 14th and 21st day.
Results :
Results are as follows.
1. All the experimental groups were improved compared with control group in plantar test.
2. All the experimental groups were improved compared with control group in touch test for sensory evaluator.
3. All the experimental groups were significantly decreased compared with control group in prostaglandin E2.
4. In histological observations, knee joint in all the experimental groups were improved compared with control group.
5. In immunological observations, all the experimental groups were significantly decreased compared with control group in COX-1, 2.
Conclusions :
It can be suggested that Bee venom and Cervi Cornu Parvum pharmacoacupuncture may improve motor behavior, hematological, histological and immunological findings in MIA-induced osetoarthritis rats. Especially, combination of these two treatments will be somewhat better in osteoarthritis recovery and motor function improvement.
The purpose of this study was to investigate the effects of Bee Venom (BV) and Cervi Cornu Parvum pharmacoacupuncture (CC) in monosodium iodide induced arthritis rats.
Methods :
The subjects were divided into 5 groups ; Normal, Control (no treatment after MIA), BV (Bee Venom pharmacoacupuncture 100 ㎕ daily at Dokbi (ST35) after inducing MIA), CC (Cervi Cornu Parvum pharmacoacupuncture 100 ㎕ daily at Dokbi (ST35) after inducing MIA) and BV+CC (Bee Venom pharmacoacupuncture and Cervi Cornu Parvum pharmacoacupuncture 100 ㎕ daily at Dokbi (ST35) after inducing MIA).
After each operation, the present author observed the motor behavior recovery, hematological (Prostaglandin E2, AST, ALT), histological and immunological changes. Rats were tested at the 7th, 14th and 21st day.
Results :
Results are as follows.
1. All the experimental groups were improved compared with control group in plantar test.
2. All the experimental groups were improved compared with control group in touch test for sensory evaluator.
3. All the experimental groups were significantly decreased compared with control group in prostaglandin E2.
4. In histological observations, knee joint in all the experimental groups were improved compared with control group.
5. In immunological observations, all the experimental groups were significantly decreased compared with control group in COX-1, 2.
Conclusions :
It can be suggested that Bee venom and Cervi Cornu Parvum pharmacoacupuncture may improve motor behavior, hematological, histological and immunological findings in MIA-induced osetoarthritis rats. Especially, combination of these two treatments will be somewhat better in osteoarthritis recovery and motor function improvement.
관련된 글
- 임상 경험방 무릎관절염 빈용
- 임상 경험방 류마토이드 관절염 빈용
- 회원임상례 등업용 슬관절 통증(비만,부종형)
- 회원임상례 실열성 슬관절통(등업용) *1
- 회원임상례 (등업용)노인 슬안풍 *1
- 보험 정보 오적산 - 건강보험 적응증
- 침구 처방집 [월오] 火 대상포진,화상,자상,통풍,관절염,산후
- 침구 처방집 [월오] 足 각종한냉,사지냉,수족냉,피비,맥비,통풍,육위,기비,하지무력,사지무력,좌골신경통,염좌,관절염
- 침구 처방집 [월오] 骨 척추측만증,강직성척추염,골절,골비,골다공증,관절염,백호역절풍
- 회원임상례 관절염의 치료(등업용) *1
- 회원임상례 슬관절염 - 빈소산 가미
- 임상 경험방 [축심여]비증 痺症
- 임상 경험방 [臨床小考] 무릎관절의 痛症 *2
- 임상 경험방 류마티스성 관절염 - 가미영선제통음
- 임상 경험방 관절염 - 가미청염탕
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